Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0008rdr32 | Emerging Reproductive Technology | REDR2014

Inducing pluripotency in livestock somatic cells to enhance genome-editing opportunities

Liu Jun , Taheri-Ghahfarokhi Amir , Verma Paul John

Abstract. Although the manipulation of animal genomes has a history of more than three decades, there are only a few of the reported genetically modified (GM) animals that have passed safety regulations and found their way through to market. The production and safety regulations of GM livestock are hindered by a variety of issues, most importantly, lack of embryonic stem cells (ESC) in livestock species and concerns around the nature and biosafety of the genom...